---
product_id: 3048441
title: "Zymox Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats"
price: "€ 67.54"
currency: EUR
in_stock: true
reviews_count: 13
url: https://www.desertcart.at/products/3048441-zymox-advanced-formula-otic-plus-enzymatic-ear-solution-for-dogs
store_origin: AT
region: Austria
---

# Gentle, no pre-cleaning needed LP3 Enzyme System for biofilm breakdown 1% Hydrocortisone for itch relief Zymox Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats

**Price:** € 67.54
**Availability:** ✅ In Stock

## Summary

> 🐾 Keep your pet’s ears happy and infection-free—because they deserve the best care, always.

## Quick Answers

- **What is this?** Zymox Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats
- **How much does it cost?** € 67.54 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.at](https://www.desertcart.at/products/3048441-zymox-advanced-formula-otic-plus-enzymatic-ear-solution-for-dogs)

## Best For

- Customers looking for quality international products

## Why This Product

- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Instant Itch Relief:** Contains 1% Hydrocortisone to soothe redness and irritation fast—because your pet deserves comfort now.
- • **All-Age Pet Friendly:** Formulated for dogs and cats of all ages, making it the go-to ear care solution for your entire fur family.
- • **No Pre-Cleaning Hassle:** Safe, gentle formula that works without painful pre-cleaning, perfect for sensitive or swollen ears.
- • **Biofilm-Busting Enzymes:** Advanced LP3 Enzyme System targets stubborn microorganisms and biofilms for deep ear cleansing.
- • **Vet-Approved Alternative:** Natural enzymatic action offers a powerful, medication-free option to combat resistant germs, fungi, and yeast.

## Overview

Zymox Advanced Formula Otic Plus is a clinically proven enzymatic ear solution for dogs and cats that combines the LP3 Enzyme System with 1% Hydrocortisone to effectively break down biofilms, relieve itching, and soothe redness without the need for pre-cleaning. Suitable for pets of all ages, it offers a natural, vet-approved alternative to traditional medications, helping prevent stubborn ear infections caused by bacteria, fungi, and yeast.

## Description

desertcart.com : Zymox Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats | with 1% Hydrocortisone, 1.25oz : Pet Ear Care Supplies : Pet Supplies

Review: The most awesome item on desertcart - My poor goldendoodle has had chronic ear infections since she got anaplasmosis from a tick bite (while on simpirica trio!). The last one in January turned antibiotic resistant. Every time we bring her to the vet, they give keto solution or otic. Her ears were so swollen the stuff doesn’t even get in there! They put her on steroids that made her crazy and still the infection turned worse. The keto solution sits in there making it a wet environment (if they are swollen some will seep down and they can’t shake it out due to swelling, or it just sits on the outside making the ear moist in general), perfect for fungus and bacteria to breed. After thousands of dollars and 3 vets all wanting to do things that don’t work or fix the CAUSE, I decided to not put any more cleaning fluids in (thank goodness for AI helping me make this decision) and just opt for this product when she starts getting itchy which is maybe once a month on air quality alert days. After her last course of topical, oral antibiotics and steroids which usually gave her two weeks of clear ears, I was prepared for another battle. She had 30 days of doxy, 14 days of another one and 7 days of another antibiotic! This destroyed her immune system. All of this because her Simpirica Trio did not work that is 200 for 6 pills (is this a scam?). And vets are not motivated to fix things since they would not have a job without chronic issues. I knew it would be rough. 2 weeks after treatment, like clockwork, her ears started back up. Instead of cleaning them more and taking her back to the vet, I got this stuff. Bam! It’s been 7 months without an infection. I also put her on Proplan fortiflora, proviable probiotics and I make sure her food doesn’t have corn, soy, wheat, or a lot of rice. A lot of the foods that VETS recommend are loaded with filler carbs! Carbs feed bacteria and yeast! Dogs need carbs, obviously just like we do but quality is important. Her food has better carbs like carrots and fruits so she still has energy. She still has itchy days because we cannot control all of her variables and she is still healing from the anaplasmosis, but dang this stuff works to keep her out of the vet and treatments that not only didn’t help, but made it worse. This actually worked to prevent infection and the probiotics have been instrumental in helping her overall immune system. Not only did it prevent infection for her but anytime she gets itchy, it helps in a matter of minutes and she can’t shake it out, it’s easy to drop in and thick. Would be nice to have a dropper bc it’s like a best guess on how much but what I’ve learned is that the sooner you get to it, the less you need and you can spot treat once it is totally clear. Life changing product when you love your pupper more than life. Worth every cent. I hope this review helps at least one other puppy and their pawrents that worry over them. Yes, bring your pets to the vet, but question them, and look for solutions rather than just going along with the plan. Find another vet that actually wants to prevent the problem, not just cytopoint it! Research it. AI is phenomenal now and we don’t just have to watch our pets suffer bc vets only have 15 min to talk to you; we can go in with questions and come to a holistic, preventative solution rather than just throwing antibiotics or allergy shots at everything.
Review: Great product - I am extremely happy with this product. My dog’s ears have cleared up much faster than I expected. It’s is very easy to apply, with it being thicker than most liquids. And it’s nice that when my dog shakes her head, the medicine doesn’t go all over her. It gave her relief from discomfort and itching after just a few treatments. I will definitely be keeping this medication on hand.

## Features

- Cat and dog ear cleaner, soothes recurrent ear issues, itching and redness, for pets of all ages
- Relief from stubborn ear problem-causing microorganisms that form complex, irritating biofilms
- Gentle formula helps relieve painful ear issues caused by resistant germs, fungi and yeast
- Pet ear solution, no pre-cleaning of painful ears needed; safe, natural alternative to medication
- LP3 Enzyme System to help clear ear exudate; 1% Hydrocortisone for itchy ears

## Technical Specifications

| Specification | Value |
|---------------|-------|
| Customer Reviews | 4.7 out of 5 stars 15,420 Reviews |

## Images

![Zymox Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats - Image 1](https://m.media-amazon.com/images/I/512WnsXPqIL.jpg)

## Questions & Answers

**Q: How is Zymox Plus different from Zymox (with the blue label)?  both say 1.0 hydrocortisone.**
A: My veterinarian said just to use the regular Zymox. It’s $10 cheaper and has the exact same ingredient. I looked it up myself. You can see the active ingredient in the inactive ingredient. Everything is the same.

It’s kind of like the namebrand Excedrin. They they packaged their product in different ways. They have Excedrin for headaches Excedrin for migraine. Exactly the same product. A lot of companies do that apparently.

Hope this helps

**Q: how do you get all the wax off the inside of the ears where it flushes out from the ear drops**
A: This is a bit thicker, kind of like the consistency of neosporin, so if your dogs ears are really wax-y right now, I would suggest doing a light cleaning before putting this in the ears. Once you put the zymox into the ear, rub your dogs ears kind of in a circular motion to help massage the solution down into the ear canal, and then just let it sit and do it's thing. Over time there will be less wax build up to clean out before applying the ointment. I now put it in my dogs ears about once every 10 to 15 days, just as maintenance and care, without needing any wax clean up before hand or afterwards.

**Q: Is this supposed to be liquidy/thin like water (not thick)? What I received is a different consistency than the thicker regular zymox I'm used to.**
A: I ordered and received a bottle this week and the solution is much thinner than the previous zymox plus otic-hc advanced formula bottles I've ordered. I haven't used it yet but just by shaking the bottle I can tell it is very liquidy compared to the bottle I have left over. I also compared the boxes and the box I received this week looks different as well. The font is different and the box has a different texture. I also read the paper inside and noticed a major typo on the one I just received. Instead of spelling "externa" they spelled "exernna" 🤦🏽‍♀️ The boxes have different lot numbers and the box that I have already opened has a later expiration date than the box I just received. I hope they didn't send me a knock off. This enzymatic solution usually works wonders on my Boxer and completely cures her ear infections when I use it as directed. I will update you on the effectiveness of the bottle I just received after I use it.

**Q: is this the same as Mometamax 15g**
A: No Different item Mometamax is stronger and is prescription medication.

## Customer Reviews

### ⭐⭐⭐⭐⭐ The most awesome item on Amazon
*by A***T on July 28, 2026*

My poor goldendoodle has had chronic ear infections since she got anaplasmosis from a tick bite (while on simpirica trio!). The last one in January turned antibiotic resistant. Every time we bring her to the vet, they give keto solution or otic. Her ears were so swollen the stuff doesn’t even get in there! They put her on steroids that made her crazy and still the infection turned worse. The keto solution sits in there making it a wet environment (if they are swollen some will seep down and they can’t shake it out due to swelling, or it just sits on the outside making the ear moist in general), perfect for fungus and bacteria to breed. After thousands of dollars and 3 vets all wanting to do things that don’t work or fix the CAUSE, I decided to not put any more cleaning fluids in (thank goodness for AI helping me make this decision) and just opt for this product when she starts getting itchy which is maybe once a month on air quality alert days. After her last course of topical, oral antibiotics and steroids which usually gave her two weeks of clear ears, I was prepared for another battle. She had 30 days of doxy, 14 days of another one and 7 days of another antibiotic! This destroyed her immune system. All of this because her Simpirica Trio did not work that is 200 for 6 pills (is this a scam?). And vets are not motivated to fix things since they would not have a job without chronic issues. I knew it would be rough. 2 weeks after treatment, like clockwork, her ears started back up. Instead of cleaning them more and taking her back to the vet, I got this stuff. Bam! It’s been 7 months without an infection. I also put her on Proplan fortiflora, proviable probiotics and I make sure her food doesn’t have corn, soy, wheat, or a lot of rice. A lot of the foods that VETS recommend are loaded with filler carbs! Carbs feed bacteria and yeast! Dogs need carbs, obviously just like we do but quality is important. Her food has better carbs like carrots and fruits so she still has energy. She still has itchy days because we cannot control all of her variables and she is still healing from the anaplasmosis, but dang this stuff works to keep her out of the vet and treatments that not only didn’t help, but made it worse. This actually worked to prevent infection and the probiotics have been instrumental in helping her overall immune system. Not only did it prevent infection for her but anytime she gets itchy, it helps in a matter of minutes and she can’t shake it out, it’s easy to drop in and thick. Would be nice to have a dropper bc it’s like a best guess on how much but what I’ve learned is that the sooner you get to it, the less you need and you can spot treat once it is totally clear. Life changing product when you love your pupper more than life. Worth every cent. I hope this review helps at least one other puppy and their pawrents that worry over them. Yes, bring your pets to the vet, but question them, and look for solutions rather than just going along with the plan. Find another vet that actually wants to prevent the problem, not just cytopoint it! Research it. AI is phenomenal now and we don’t just have to watch our pets suffer bc vets only have 15 min to talk to you; we can go in with questions and come to a holistic, preventative solution rather than just throwing antibiotics or allergy shots at everything.

### ⭐⭐⭐⭐⭐ Great product
*by H***N on August 24, 2026*

I am extremely happy with this product. My dog’s ears have cleared up much faster than I expected. It’s is very easy to apply, with it being thicker than most liquids. And it’s nice that when my dog shakes her head, the medicine doesn’t go all over her. It gave her relief from discomfort and itching after just a few treatments. I will definitely be keeping this medication on hand.

### ⭐⭐⭐⭐⭐ Works every time!
*by A***B on August 23, 2026*

About twice a year, our dog’s ears need more than just a wipe, and that’s when we turn to this product. It has successfully knocked out any and all brewing ear infections due to environmental allergies, swimming, or whatever else. Not having to pre-clean the ear means less discomfort when treating. The gel formula seems to be tolerated better by our dog than the liquid solutions, and between the post-application head shake and wiping of excess gel, it basically coats all surfaces of the inside of the ear to effectively treat the entirety. Hydrocortisone also relieves itch and calms sore, red, inflamed ears, making each subsequent application easier and less painful. If you use this please be sure to use the product for the entire duration that is recommended. This is not a one and done product. It takes time and consistency for these enzymes to fully treat, break down all the gunk, and clean out the ear. If you apply this for only 1 or 2 days, wax and debris will still remain deep inside the ear and nothing will be solved. Don’t be lazy.

## Frequently Bought Together

- Zymox Advanced Formula Otic Plus Enzymatic Ear Solution for Dogs and Cats with 1% Hydrocortisone, 1.25oz
- Zymox Advanced Enzymatic Ear Wipes for Dogs and Cats - for Dirty, Waxy, Smelly Ears - Premium Strength Ear Cleaner Wipes - Non-Irritating - Hypoallergenic - 100 ct
- Zymox Ear Cleanser Solution for Dogs and Cats, 4oz

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*Product available on Desertcart Austria*
*Store origin: AT*
*Last updated: 2026-09-04*